Over the years, a handful of players have represented both clubs, and the Luton News have picked 15 to have do so in the gallery below.
13. Teden Mengi
Born in Manchester, the centre half spent over a decade at Old Trafford when coming through the ranks. Played two first team outings in Europe for the Red Devils, and had loan spells with Derby and Birmingham, snapped up by Luton in the summer. Has played seven matches for the Hatters so far, impressing in Sunday's 1-1 draw with Liverpool. Photo: Liam Smith
14. Simon Davies
Born in Cheshire, he came through at United, part of the famous Class of 92 squad that won the FA Youth Cup. Played 20 times for the first team, scoring once, as the Wales international moved to Luton in 1997 for £150,000. Couldn't quite hit the heights expected at Kenilworth Road, making 30 appearances with one goal, leaving for Macclesfield just over a year later. Finished his playing days back in Wales and now Academy Director.at Tottenham Hotspur. Photo: Hatters Heritage
15. Graeme Tomlinson
After starting out with Bradford, he was signed by Manchester United for a fee of £100,000 in 1994. Only managed two sub outings for the Red Devils in the League Cup, as he was loaned to Luton in 1996. Played seven matches, but was unable to find the target for the Hatters as unfortunately on his full debut, suffered a broken leg. Left Old Trafford for Macclesfield in 1998 and played for Exeter before dropping into non-league football. Photo: Hatters Heritage