With a fully fit squad barring striker Cauley Woodrow, here is how manager Rob Edwards could set his side up to take on the Wearsiders.
5. LCB: Amari’i Bell
Easily one of the unsung heroes this term, such has been his effortless and slick work in his new role at left centre half. Raiding runs forward have been a real feature of Luton's ability to bring the ball out from the back. Photo: Liam Smith
6. LWB: Alfie Doughty
Played an hour against Hull on Monday before being withdrawn for teenager Joe Johnson. Will no doubt be on the flank at Sunderland again and looking to score his second of the season against the Black Cats. Photo: Liam Smith
7. CDM: Marvelous Nakamba
Who else? Zimbabwe international has been simply tremendous in the holding role since joining from Aston Villa and a massive favourite with fans already. Photo: Liam Smith
8. CM: Pelly-Ruddock Mpanzu
After the heartbreak of missing out on the play-offs last season, this is Mpanzu's time to shine as he looks to spearhead the Hatters to the Premier League. Photo: Liam Smith